产品货号：
Z38400
中文名称：
TIGIT抗体
英文名称：
Anti-TIGIT Antibody (Clone#7E5)
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TIGIT Antibody (Clone#7E5) |
| 指标别名 | T-cell immunoreceptor with Ig and ITIM domains;VSIG9;VSTM3;WUCAM |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | ELISA,IHC,ICC,IF,FCM |
| 基因名称 | TIGIT |
| 克隆号 | 7E5 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | TIGIT antibody was raised against the extracellular domain of human TIGIT. |
| 计算分子量 | 26kDa |
| 成分 | TIGIT Antibody is supplied in PBS containing 0.02% sodium azide and 50% glycerol. |
| 纯化方式 | TIGIT Antibody is supplied as protein A purified IgG2b. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The T cell immunoreceptor with Ig and ITIM domains (TIGIT) is a member of the PVR (poliovirus receptor) family of immunoglobin proteins.It is expressed on several classes of T cells including follicular B helper T cells (TFH).TIGIT has been shown to bind PVR with high affinity;this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses (1).Similar to other immune checkpoint proteins such as PD-1,TIGIT is upregulated on exhausted T cells in chronic viral infections and cancer.Blockade of both TIGIT and PD-1 pathways leads to tumor rejection in mice suggesting that it may be of therapeutic use against cancer (2). |
| Uniprot ID | Q495A1 |
| 基因名全称 | T-cell immunoreceptor with Ig and ITIM domains |
| 蛋白名全称 | T-cell immunoreceptor with Ig and ITIM domains |
| 推荐稀释比 | TIGIT antibody can be used for immunohistochemistry starting at 2 ～ 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Immunohistochemistry in human samples;Immunocytochemistry in human samples;Immunofluorescence in human samples and Flow Cytometry in human samples.All other applications and species not yet tested. |
相关搜索：TIGIT抗体，TIGIT单抗，Anti-TIGIT Antibody (Clone#7E5)